CAS No. 134523-03-8 - CAS No. 134523-03-8 Specificaton & Trade Terms
| Model | CAS No. 134523-03-8 |
|---|
| Place Of Origin | china |
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| Price Term | EX-Work |
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| Payment Term | T/T |
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【Appearance】
White Crystalline Powder
【Melting Point】176-178°C
【Flash Point】390.6 °C
【Water】Slightly soluble
【Usage】
A selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia
【Biological Activity】
Potent HMG-CoA reductase inhibitor (IC 50 = 8 nM). Reduces circulating LDL-C by inhibiting cholesterol biosynthesis and inducing expression of LDL receptors. Inhibits smooth muscle cell proliferation in vitro and exhibits antinociceptive effects in the inflammatory hypernociception model.
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